4-Bromo-1,5-dimethyl-1H-pyrazole-4-carboxylic acid
1H-Pyrazole-3-carboxylic acid, 4-bromo-1,5-dimethyl-
CAS: 5775-91-7
Molecular Formula: C6H7BrN2O2
4-Bromo-1,5-dimethyl-1H-pyrazole-4-carboxylic acid - Names and Identifiers
4-Bromo-1,5-dimethyl-1H-pyrazole-4-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C6H7BrN2O2 |
| Molar Mass | 219.04 |
| Density | 1.80±0.1 g/cm3(Predicted) |
| Melting Point | 194 °C |
| Boling Point | 344.0±42.0 °C(Predicted) |
| pKa | 2.77±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD02090877 |
4-Bromo-1,5-dimethyl-1H-pyrazole-4-carboxylic acid - Introduction
Acid, 4-bromo-1, 5-dimethanol-is a compound whose chemical formula is C7H8BrNO2.
Nature:
1. Appearance: acid, 4-bromo-1,5-dimethyl-white solid.
2. Melting point: The melting point of the compound is between 128-130°C.
3. Solubility: It is soluble in some organic solvents, such as ethanol and dichloromethane, but insoluble in water.
Use:
Acid, 4-bromo-1,5-dimethyl-has certain application value in organic synthesis, and is mainly used to construct the skeleton of organic molecules and guide reactions. It can be used as an intermediate for the synthesis of pesticides, pharmaceuticals and dyes.
Preparation Method:
acid, 4-bromo-1,5-dimethyl-can be synthesized by the following steps-:
1. First, methyl methacrylate and aniline are reacted under the catalysis of alkali to prepare 1,5-dimethyl-1H-pyrazole.
2. 1,5-dimethyl -1H-pyrazole is reacted with hydrogen bromide in the presence of acetic acid to generate 4-bromo-1, 5-dimethyl -1H-pyrazole.
3. Finally, 4-bromo-1, 5-dimethyl-1H-pyrazole is reacted with sodium hydroxide or sodium carbonate to generate acid, 4-bromo-1,5-dimethy-.
Safety Information:
Regarding the safety of acid, 4-bromo-1,5-dimethyl-, the following matters need to be noted:
1. the compound may be irritating to the eyes, skin and respiratory system, please avoid direct contact.
2. During use, avoid inhaling the dust or vapor of the solution.
3. During operation and storage, good ventilation and personal protective measures should be taken, such as wearing protective glasses, gloves and appropriate protective clothing.
4. If you come into contact with this compound, immediately flush the affected area with plenty of water and consult your doctor's advice.
This information is for reference only. Please read and follow the safety data sheet of the relevant chemical before use.
Nature:
1. Appearance: acid, 4-bromo-1,5-dimethyl-white solid.
2. Melting point: The melting point of the compound is between 128-130°C.
3. Solubility: It is soluble in some organic solvents, such as ethanol and dichloromethane, but insoluble in water.
Use:
Acid, 4-bromo-1,5-dimethyl-has certain application value in organic synthesis, and is mainly used to construct the skeleton of organic molecules and guide reactions. It can be used as an intermediate for the synthesis of pesticides, pharmaceuticals and dyes.
Preparation Method:
acid, 4-bromo-1,5-dimethyl-can be synthesized by the following steps-:
1. First, methyl methacrylate and aniline are reacted under the catalysis of alkali to prepare 1,5-dimethyl-1H-pyrazole.
2. 1,5-dimethyl -1H-pyrazole is reacted with hydrogen bromide in the presence of acetic acid to generate 4-bromo-1, 5-dimethyl -1H-pyrazole.
3. Finally, 4-bromo-1, 5-dimethyl-1H-pyrazole is reacted with sodium hydroxide or sodium carbonate to generate acid, 4-bromo-1,5-dimethy-.
Safety Information:
Regarding the safety of acid, 4-bromo-1,5-dimethyl-, the following matters need to be noted:
1. the compound may be irritating to the eyes, skin and respiratory system, please avoid direct contact.
2. During use, avoid inhaling the dust or vapor of the solution.
3. During operation and storage, good ventilation and personal protective measures should be taken, such as wearing protective glasses, gloves and appropriate protective clothing.
4. If you come into contact with this compound, immediately flush the affected area with plenty of water and consult your doctor's advice.
This information is for reference only. Please read and follow the safety data sheet of the relevant chemical before use.
Last Update：2024-04-09 21:01:54
